Structure de mise en forme 2 colonnes

Methodology and workflow

In the long term, FLIP aims to lay the foundations for the future of NAFLD research in Europe and create a European Collaborative Research Network on NAFLD.
In the long term, FLIP aims to lay the foundations for the future of NAFLD research in Europe and create a European Collaborative Research Network on NAFLD.


Overall, FLIP will study mechanisms of progression and suggest preventive and therapeutic strategies. The main deliverables are:

Creation of a prospective European cohort of patients with standardised inclusion criteria and histologically proven NAFLD/NASH

Creation of a prospective European observatory of hepatocellular carcinoma in NASH

Identification of novel epidemiological determinants for NAFLD in adolescence and adulthood

Identification of clinical correlates and mechanisms of progression in NAFLD (spanning all the steps of the disease and answering key issues dealing with the interplay of metabolic, inflammatory and fibrotic factors in the initiation and perpetuation of liver injury)

Validation of improved diagnostic and prognostic markers for NAFLD

Validation of consensual histological classification of NAFLD/ NASH

Improved implementation of preventative strategies in NAFLD